The use of antiretroviral medication administered prior to sexual exposure pre-exposure prophylaxis, PREP to reduce the risk of HIV infection is under study in high-risk populations. However, all studies that have controlled for competing risk behaviors 35,36,38,40,69,70 have concluded that oral-vaginal sex is extremely low risk. Most of the infectious organisms are transferred by direct contact with a sore or lesion on the genitals or mouth. Not everyone will open a discussion about safer sex with a health care provider.
There is not yet a clear understanding of the probability of superinfection at the individual or population level, nor do we fully understand its impact on the long-term health of HIV-infected individuals. Early male-to-male transmission studies consistently failed to demonstrate an increased risk of HIV infection associated with the practice of oral-penile sex. Some STDs can also be transferred by direct, nonsexual contact with infected tissues or fluids. Reasons for Condom Failure As the results of HIV transmission studies indicate, being made of material impermeable to HIV in a laboratory ie, latex or polyurethane is not sufficient to ensure that condoms will provide complete protection during real-life usage.